IPS cell line derivation & Differentiation service

Induced pluripotent stem (IPS) cells can be directly derived from somatic cells by ” reprogramming ” technology. IPS cells, similarly to embryonic stem (ES) cells, are capable of unlimited proliferation in vitro and still maintain the ability to differentiate into any clinically relevant adult cell type, including nerve, heart, of liver.

In this capacity, IPS cells have widespread clinical potential for modelling disease and helping develop treatments for cardiac disease, diabetes, and various neurodegenerative disorders or injuries. By using iPS cells, we are able to test how different patients might respond to new drugs.

IPS cell line derivation service

We offer to generate IPS cell lines from healthy and diseased individuals:
- Maintenance, freezing, and expanding IPS cell lines
- Characterisation of IPS cell lines for their pluripotency and differentiation ability by morphology, immunocytochemistry, quantitative real-time PCR, transcriptome and/or genome sequencing; or based on special request.
- Production of 1-2 million iPS cells (1-2 cryovials; 1 million cells/vial; Data & Report)
- Optional Pathogen Testing Service is also available.

IPS cell differentiation service:

We offer differentiating IPS cell lines to multiple cell types including cardiac, neural, endothelial and keratinocyte. Cell types differentiated from iPS cells ensure the convenience of in vitro stem cell-based models with the relevance of primary cells but without the lot-to-lot variability issues and derivation associated with primary human cells.

Production of 2 million differentiated cells, Data & Report
Characterisation of derivative cell types based on their lineage-specific marker analyses
Optional Pathogen Testing Service is also available
Development and validation of custom in vitro bioassays based on IPS cells.

Other Service

Need help?

If the service you are looking for is not listed, or you require specialist modification to an existing process, please do get in touch, and our team will build a bespoke offering with you.